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Vyvanse is a central nervous system stimulant prescription medicine. It is used for the treatment of
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Vyvanse (lisdexamfetamine dimesylate) is designed as a capsule for once-a-day oral administration.
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Vyvanse is a pro-drug of dextroamphetamine. After oral administration, lisdexamfetamine dimesylate
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mphetamines are noncatecholamine sympathomimetic amines with CNS stimulant activity.
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The mode of therapeutic action in Attention-Deficit/Hyperactivity Disorder (ADHD) is not known.
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DOSAGE FORMS AND STRENGTHS
1. Capsules 10 mg: pink body/pink cap (imprinted with S489 and 10 mg)
2. Capsules 20 mg: ivory body/ivory cap (imprinted with S489 and 20 mg)
3. Capsules 30 mg: white body/orange cap (imprinted with S489 and 30 mg)
4. Capsules 40 mg: white body/blue green cap (imprinted with S489 and 40 mg)
5. Capsules 50 mg: white body/blue cap (imprinted with S489 and 50 mg)
6. Capsules 60 mg: aqua blue body/aqua blue cap (imprinted with S489 and 60 mg)
7. Capsules 70 mg: blue body/orange cap (imprinted with S489 and 70 mg)
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General information about Vyvanse
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If you would like more information, talk with your doctor.
You can ask your doctor or pharmacist for information about Vyvanse that was written for
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General: The least amount of Vyvanse feasible should be prescribed or dispensed at one time in
order to minimize the possibility of overdosage. Vyvanse should be used with caution
in patients who use other sympathomimetic drugs. Tics: Amphetamines have been reported to
exacerbate motor and phonic tics and Tourette’s syndrome.
Therefore, clinical evaluation for tics and Tourette’s syndrome in children and their families
should precede use of stimulant medications.
Information for Patients: Amphetamines may impair the ability of the patient to engage in
potentially hazardous activities such as operating machinery or vehicles; the patient should
therefore be cautioned accordingly.
Prescribers or other health professionals should inform patients, their families, and
their caregivers about the benefits and risks associated with treatment with lisdexamfetamine
and should counsel them in its appropriate use. A patient Medication Guide is available for Vyvanse.
The prescriber or health professional should instruct patients, their families, and their caregivers to read the Medication
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to discuss the contents of the Medication Guide and to obtain answers to any questions they may have.
The complete text of the Medication Guide is reprinted at the end of this document.
ADVERSE REACTIONS
Adolescents, and/or adults with ADHD were anorexia, anxiety, decreased appetite, decreased weight,
diarrhea, dizziness, dry mouth, irritability, insomnia, nausea, upper abdominal pain, and vomiting.
Most common adverse reactions (incidence 5% and at a rate at least twice placebo) in adults with
BED were dry mouth, insomnia, decreased appetite, increased heart rate, constipation, feeling
jittery, and anxiety.
WARNINGS AND PRECAUTIONS
Serious Cardiovascular Reactions: Sudden death in children and adolescents with serious heart
problems, as well as sudden death, stroke, and myocardial infarction in adults reported.
Avoid use in patients with known structural cardiac abnormalities, cardiomyopathy, serious
heart arrhythmia, or coronary artery disease.
Blood Pressure and Heart Rate Increases: Monitor blood pressure and pulse. Consider benefits
and risks before use in patients for whom blood pressure increases may be problematic.
Psychiatric Adverse Reactions: May cause psychotic or manic symptoms in patients with
no prior history, or exacerbation of symptoms in patients with pre-existing psychosis.
Evaluate for bipolar disorder prior to stimulant use. Suppression of Growth: Monitor height and weight
in pediatric patients during treatment.
Peripheral Vasculopathy, including Raynaud’s phenomenon: Stimulants are associated with
peripheral vasculopathy, including Raynaud’s phenomenon.
Careful observation for digital changes is necessary during treatment with stimulants. Wikipedia
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