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Vyvanse is a central nervous system stimulant prescription medicine. It is used for the treatment of

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Vyvanse (lisdexamfetamine dimesylate) is designed as a capsule for once-a-day oral administration.

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Vyvanse is a pro-drug of dextroamphetamine. After oral administration, lisdexamfetamine dimesylate

is rapidly absorbed from the gastrointestinal tract and converted to dextroamphetamine, which is responsible

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mphetamines are noncatecholamine sympathomimetic amines with CNS stimulant activity.

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The mode of therapeutic action in Attention-Deficit/Hyperactivity Disorder (ADHD) is not known.

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DOSAGE FORMS AND STRENGTHS

1. Capsules 10 mg: pink body/pink cap (imprinted with S489 and 10 mg)

2. Capsules 20 mg: ivory body/ivory cap (imprinted with S489 and 20 mg)

3. Capsules 30 mg: white body/orange cap (imprinted with S489 and 30 mg)

4. Capsules 40 mg: white body/blue green cap (imprinted with S489 and 40 mg)

5. Capsules 50 mg: white body/blue cap (imprinted with S489 and 50 mg)

6. Capsules 60 mg: aqua blue body/aqua blue cap (imprinted with S489 and 60 mg)

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General information about Vyvanse
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General: The least amount of Vyvanse feasible should be prescribed or dispensed at one time in

order to minimize the possibility of overdosage. Vyvanse should be used with caution

in patients who use other sympathomimetic drugs. Tics: Amphetamines have been reported to

exacerbate motor and phonic tics and Tourette’s syndrome.

Therefore, clinical evaluation for tics and Tourette’s syndrome in children and their families

should precede use of stimulant medications.

Information for Patients: Amphetamines may impair the ability of the patient to engage in

potentially hazardous activities such as operating machinery or vehicles; the patient should

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Prescribers or other health professionals should inform patients, their families, and
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and should counsel them in its appropriate use. A patient Medication Guide is available for Vyvanse.

The prescriber or health professional should instruct patients, their families, and their caregivers to read the Medication
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to discuss the contents of the Medication Guide and to obtain answers to any questions they may have.

The complete text of the Medication Guide is reprinted at the end of this document.

ADVERSE REACTIONS

Adolescents, and/or adults with ADHD were anorexia, anxiety, decreased appetite, decreased weight,

diarrhea, dizziness, dry mouth, irritability, insomnia, nausea, upper abdominal pain, and vomiting.
Most common adverse reactions (incidence •5% and at a rate at least twice placebo) in adults with

BED were dry mouth, insomnia, decreased appetite, increased heart rate, constipation, feeling

jittery, and anxiety.

 

WARNINGS AND PRECAUTIONS

Serious Cardiovascular Reactions: Sudden death in children and adolescents with serious heart

problems, as well as sudden death, stroke, and myocardial infarction in adults reported.

Avoid use in patients with known structural cardiac abnormalities, cardiomyopathy, serious

heart arrhythmia, or coronary artery disease.

Blood Pressure and Heart Rate Increases: Monitor blood pressure and pulse. Consider benefits

and risks before use in patients for whom blood pressure increases may be problematic.

Psychiatric Adverse Reactions: May cause psychotic or manic symptoms in patients with

no prior history, or exacerbation of symptoms in patients with pre-existing psychosis.

Evaluate for bipolar disorder prior to stimulant use. Suppression of Growth: Monitor height and weight

in pediatric patients during treatment.

Peripheral Vasculopathy, including Raynaud’s phenomenon: Stimulants are associated with

peripheral vasculopathy, including Raynaud’s phenomenon.

Careful observation for digital changes is necessary during treatment with stimulants. Wikipedia