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Vyvanse is a central nervous system stimulant prescription medicine. It is used for the treatment of
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Vyvanse (lisdexamfetamine dimesylate) is designed as a capsule for once-a-day oral administration.
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Vyvanse is a pro-drug of dextroamphetamine. After oral administration, lisdexamfetamine dimesylate
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mphetamines are noncatecholamine sympathomimetic amines with CNS stimulant activity.
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DOSAGE FORMS AND STRENGTHS
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General: The least amount of Vyvanse feasible should be prescribed or dispensed at one time in
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in patients who use other sympathomimetic drugs. Tics: Amphetamines have been reported to
exacerbate motor and phonic tics and Tourette’s syndrome.
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should precede use of stimulant medications.
Information for Patients: Amphetamines may impair the ability of the patient to engage in
potentially hazardous activities such as operating machinery or vehicles; the patient should
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Prescribers or other health professionals should inform patients, their families, and
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The prescriber or health professional should instruct patients, their families, and their caregivers to read the Medication
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The complete text of the Medication Guide is reprinted at the end of this document.
Adolescents, and/or adults with ADHD were anorexia, anxiety, decreased appetite, decreased weight,
diarrhea, dizziness, dry mouth, irritability, insomnia, nausea, upper abdominal pain, and vomiting.
Most common adverse reactions (incidence 5% and at a rate at least twice placebo) in adults with
BED were dry mouth, insomnia, decreased appetite, increased heart rate, constipation, feeling
jittery, and anxiety.
WARNINGS AND PRECAUTIONS
Serious Cardiovascular Reactions: Sudden death in children and adolescents with serious heart
problems, as well as sudden death, stroke, and myocardial infarction in adults reported.
Avoid use in patients with known structural cardiac abnormalities, cardiomyopathy, serious
heart arrhythmia, or coronary artery disease.
Blood Pressure and Heart Rate Increases: Monitor blood pressure and pulse. Consider benefits
and risks before use in patients for whom blood pressure increases may be problematic.
Psychiatric Adverse Reactions: May cause psychotic or manic symptoms in patients with
no prior history, or exacerbation of symptoms in patients with pre-existing psychosis.
Evaluate for bipolar disorder prior to stimulant use. Suppression of Growth: Monitor height and weight
in pediatric patients during treatment.
Peripheral Vasculopathy, including Raynaud’s phenomenon: Stimulants are associated with
peripheral vasculopathy, including Raynaud’s phenomenon.
Careful observation for digital changes is necessary during treatment with stimulants. Wikipedia